Microbial Coculture for Flavonoid Synthesis

Peng Xu; Monireh Marsafari; Jian Zha; Mattheos Koffas

doi:10.1016/j.tibtech.2020.01.008

Microbial Coculture for Flavonoid Synthesis

Peng Xu^*, Monireh Marsafari, Jian Zha, Mattheos Koffas

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

39 Scopus citations

Abstract

Flavonoids are plant-derived natural products with human health-promoting benefits. The modularity and complexity of the flavonoid biosynthetic pathway allow us to leverage the metabolic characteristics of distinct microbial hosts and install structural functionalities beyond what monocultures can achieve. We discuss the promising future of applying microbial cocultures to improve the cost-efficiency and diversity of flavonoid biosynthesis.

Original language	English
Pages (from-to)	686-688
Number of pages	3
Journal	Trends in Biotechnology
Volume	38
Issue number	7
DOIs	https://doi.org/10.1016/j.tibtech.2020.01.008
State	Published - Jul 2020
Externally published	Yes

Keywords

flavonoids
host selection
microbial coculture
pathway efficiency
population dynamics
structural diversity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tibtech.2020.01.008

Cite this

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title = "Microbial Coculture for Flavonoid Synthesis",

abstract = "Flavonoids are plant-derived natural products with human health-promoting benefits. The modularity and complexity of the flavonoid biosynthetic pathway allow us to leverage the metabolic characteristics of distinct microbial hosts and install structural functionalities beyond what monocultures can achieve. We discuss the promising future of applying microbial cocultures to improve the cost-efficiency and diversity of flavonoid biosynthesis.",

keywords = "flavonoids, host selection, microbial coculture, pathway efficiency, population dynamics, structural diversity",

author = "Peng Xu and Monireh Marsafari and Jian Zha and Mattheos Koffas",

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year = "2020",

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AU - Xu, Peng

AU - Marsafari, Monireh

AU - Zha, Jian

AU - Koffas, Mattheos

PY - 2020/7

Y1 - 2020/7

N2 - Flavonoids are plant-derived natural products with human health-promoting benefits. The modularity and complexity of the flavonoid biosynthetic pathway allow us to leverage the metabolic characteristics of distinct microbial hosts and install structural functionalities beyond what monocultures can achieve. We discuss the promising future of applying microbial cocultures to improve the cost-efficiency and diversity of flavonoid biosynthesis.

AB - Flavonoids are plant-derived natural products with human health-promoting benefits. The modularity and complexity of the flavonoid biosynthetic pathway allow us to leverage the metabolic characteristics of distinct microbial hosts and install structural functionalities beyond what monocultures can achieve. We discuss the promising future of applying microbial cocultures to improve the cost-efficiency and diversity of flavonoid biosynthesis.

KW - flavonoids

KW - host selection

KW - microbial coculture

KW - pathway efficiency

KW - population dynamics

KW - structural diversity

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U2 - 10.1016/j.tibtech.2020.01.008

DO - 10.1016/j.tibtech.2020.01.008

M3 - 短篇评述

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JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - 7

ER -

Microbial Coculture for Flavonoid Synthesis

Abstract

Keywords

UN SDGs

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