Abstract
Background: Carvacrol is an aromatic phenolicterpenoidwidely existingin the volatile oils of thyme, oregano, and some other aromatic plants. Recent studies have found that carvacrol possessesexcellent antibacterial activity. Thus, inorder to provide an updated information about the antibacterial potentials of carvacrolwe summarized recent publications about the antibacterial activity of carvacrol,with special attention paid to its antibacterial molecular mechanisms, includingdisruptingcellmembrane, depleting intracellular ATP, inducing reactive oxygen species, inhibiting efflux pumps, as well as suppressing two important virulence factors:biofilm and quorum sensing.In conclusion, carvacrol is a promising natural antibacterial compound with potential application in food preservation and infection.
Original language | English |
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Pages (from-to) | 71-81 |
Number of pages | 11 |
Journal | Bioactive Compounds in Health and Disease |
Volume | 1 |
Issue number | 6 |
DOIs | |
State | Published - Oct 2018 |
Externally published | Yes |
Keywords
- Antibacterialmechanisms
- Biofilm
- Carvacrol
- Quorum sensing