TY - JOUR
T1 - Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms
AU - Guo, Keying
AU - Sharma, Apoorva
AU - Toh, Rou Jun
AU - Alvárez de Eulate, Eva
AU - Gengenbach, Thomas R.
AU - Cetó, Xavier
AU - Voelcker, Nicolas H.
AU - Prieto-Simón, Beatriz
N1 - Publisher Copyright:
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2019/6/13
Y1 - 2019/6/13
N2 - The electrochemical performance of porous silicon (pSi) stabilized via thermal decomposition of acetylene gas is investigated for the first time. In this study, pSi undergoes two thermal treatments at either 525 or 800 °C, which result in hydrogen-terminated thermally hydrocarbonized pSi (THCpSi) and hydroxyl-terminated thermally carbonized pSi (TCpSi), respectively, the latter upon dipping in hydrofluoric acid to activate the surface termination. Electrochemical characterization, using cyclic voltammetry, chronocoulometry, and electrochemical impedance spectroscopy in the presence of several redox pairs, [Fe(CN)6]3/4−, [Ru(NH3)6]2/3+, and hydroquinone/quinone, is used to demonstrate the versatility and high stability to degradation of carbon-stabilized pSi nanostructures and their excellent electrochemical performance. Added to the large surface area, adjustable pore morphology and tailorable surface chemistry of THCpSi and TCpSi, these nanostructures demonstrate fast electron-transfer kinetics, providing key advantages over conventional carbon electrodes. The versatile surface chemistry of THCpSi and TCpSi offer various possibilities to introduce multiple functional groups depending on the nature of the bioreceptor to be immobilized. For proof of principle, the use of a THCpSi-based immunosensor to detect MS2 bacteriophage is demonstrated by means of electrochemical impedance spectroscopy, showing a detection limit of 4.9 pfu mL−1. Carbon-stabilized pSi structures represent a new class of nanostructured electrodes for biosensing applications.
AB - The electrochemical performance of porous silicon (pSi) stabilized via thermal decomposition of acetylene gas is investigated for the first time. In this study, pSi undergoes two thermal treatments at either 525 or 800 °C, which result in hydrogen-terminated thermally hydrocarbonized pSi (THCpSi) and hydroxyl-terminated thermally carbonized pSi (TCpSi), respectively, the latter upon dipping in hydrofluoric acid to activate the surface termination. Electrochemical characterization, using cyclic voltammetry, chronocoulometry, and electrochemical impedance spectroscopy in the presence of several redox pairs, [Fe(CN)6]3/4−, [Ru(NH3)6]2/3+, and hydroquinone/quinone, is used to demonstrate the versatility and high stability to degradation of carbon-stabilized pSi nanostructures and their excellent electrochemical performance. Added to the large surface area, adjustable pore morphology and tailorable surface chemistry of THCpSi and TCpSi, these nanostructures demonstrate fast electron-transfer kinetics, providing key advantages over conventional carbon electrodes. The versatile surface chemistry of THCpSi and TCpSi offer various possibilities to introduce multiple functional groups depending on the nature of the bioreceptor to be immobilized. For proof of principle, the use of a THCpSi-based immunosensor to detect MS2 bacteriophage is demonstrated by means of electrochemical impedance spectroscopy, showing a detection limit of 4.9 pfu mL−1. Carbon-stabilized pSi structures represent a new class of nanostructured electrodes for biosensing applications.
KW - biosensing
KW - carbon stabilization
KW - electrochemistry
KW - porous silicon
UR - http://www.scopus.com/inward/record.url?scp=85064494520&partnerID=8YFLogxK
U2 - 10.1002/adfm.201809206
DO - 10.1002/adfm.201809206
M3 - 文章
AN - SCOPUS:85064494520
SN - 1616-301X
VL - 29
JO - Advanced Functional Materials
JF - Advanced Functional Materials
IS - 24
M1 - 1809206
ER -