TY - JOUR
T1 - Nanostructures, Faceting, and Splitting in Nanoliter to Yoctoliter Liquid Droplets
AU - Guttman, Shani
AU - Kesselman, Ellina
AU - Jacob, Avi
AU - Marin, Orlando
AU - Danino, Dganit
AU - Deutsch, Moshe
AU - Sloutskin, Eli
N1 - Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/5/8
Y1 - 2019/5/8
N2 - Contrary to everyday experience, where all liquid droplets assume rounded, near-spherical shapes, the temperature-tuning of liquid droplets to faceted polyhedral shapes and to spontaneous splitting has been recently demonstrated in oil-in-water emulsions. However, the elucidation of the mechanism driving these surprising effects, as well as their many potential applications, ranging from faceted nanoparticle synthesis through new industrial emulsification routes to controlled-release drug delivery within the human body, have been severely hampered by the micron-scale resolution of the light microscopy employed to date in all in situ studies. Thus, the thickness of the interfacially frozen crystalline monolayer, suggested to drive these effects, could not be directly measured, and the low limit on the droplet size still showing these effects remained unknown. In this study, we employ a combination of super-resolution stimulated emission depletion microscopy, cryogenic transmission and freeze-fracture electron microscopy, to study these effects well into the nanometer length scale. We demonstrate the occurrence of the faceting transition in droplets spanning an incredible 12 decades in volume from nanoliters to yoctoliters and directly visualize the interfacially frozen, few nanometer thick, crystalline monolayer suggested to drive these effects. Furthermore, our measurements allow placing an upper-limit estimate on the two-dimensional Young modulus of the interfacial nanometer-thick surface crystal in the smallest droplets, providing insights into the virtually unexplored domain of nanoelasticity.
AB - Contrary to everyday experience, where all liquid droplets assume rounded, near-spherical shapes, the temperature-tuning of liquid droplets to faceted polyhedral shapes and to spontaneous splitting has been recently demonstrated in oil-in-water emulsions. However, the elucidation of the mechanism driving these surprising effects, as well as their many potential applications, ranging from faceted nanoparticle synthesis through new industrial emulsification routes to controlled-release drug delivery within the human body, have been severely hampered by the micron-scale resolution of the light microscopy employed to date in all in situ studies. Thus, the thickness of the interfacially frozen crystalline monolayer, suggested to drive these effects, could not be directly measured, and the low limit on the droplet size still showing these effects remained unknown. In this study, we employ a combination of super-resolution stimulated emission depletion microscopy, cryogenic transmission and freeze-fracture electron microscopy, to study these effects well into the nanometer length scale. We demonstrate the occurrence of the faceting transition in droplets spanning an incredible 12 decades in volume from nanoliters to yoctoliters and directly visualize the interfacially frozen, few nanometer thick, crystalline monolayer suggested to drive these effects. Furthermore, our measurements allow placing an upper-limit estimate on the two-dimensional Young modulus of the interfacial nanometer-thick surface crystal in the smallest droplets, providing insights into the virtually unexplored domain of nanoelasticity.
KW - Faceting
KW - STED
KW - cryo-electron microscopy
KW - emulsion
KW - interfacial freezing
UR - http://www.scopus.com/inward/record.url?scp=85065098150&partnerID=8YFLogxK
U2 - 10.1021/acs.nanolett.9b00594
DO - 10.1021/acs.nanolett.9b00594
M3 - 文章
C2 - 30986069
AN - SCOPUS:85065098150
SN - 1530-6984
VL - 19
SP - 3161
EP - 3168
JO - Nano Letters
JF - Nano Letters
IS - 5
ER -