@inproceedings{495d11f1141d4f7b983f072c721cb602,
title = "Milk protein nanocapsules for drug delivery",
abstract = "In the presented work we investigated the possible use of β-casein micelles as a vehicle for delivery of water-insoluble molecules, particularly drugs. Our model drug, celecoxib, was encapsulated in micelles of β-casein. Freeze-dried and resuspended micelles retained their original pre-lyophilized structure, uniform size, and morphology. Small-angle X-ray scattering (SAXS) measurements show a transition from an oblate ellipsoid to a more spherical micelle shape and an increase in the micelle size upon drug loading, and confirm no influence of drying on the dimensions, as also indicated by cryo-TEM. SAXS points to a slight increase in the micelle density after drug loading, confirming mixed micelles formation.",
keywords = "Beta-casein, Drug delivery, Micelles, Nanoencapsulation",
author = "R. Khalfin and M. Bachar and D. Danino",
year = "2011",
language = "英语",
isbn = "9781439871386",
series = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
pages = "306--309",
booktitle = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
note = "Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011 ; Conference date: 13-06-2011 Through 16-06-2011",
}