Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation

Jun Yong Chan; Huacheng Zhang; Yada Nolvachai; Yaoxin Hu; Haijin Zhu; Maria Forsyth; Qinfen Gu; David E. Hoke; Xiwang Zhang; Philip J. Marriot; Huanting Wang

doi:10.1002/anie.201810925

Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation

Jun Yong Chan, Huacheng Zhang^*, Yada Nolvachai, Yaoxin Hu, Haijin Zhu, Maria Forsyth, Qinfen Gu, David E. Hoke, Xiwang Zhang, Philip J. Marriot, Huanting Wang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

Abstract

Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high-quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework-8 (ZIF-8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l-histidine (l-His), into the framework of ZIF-8. The homochiral l-His-ZIF-8 membrane exhibits a good selectivity for the R-enantiomer of 1-phenylethanol over the S-enantiomer, showing a high enantiomeric excess value up to 76 %.

Original language	English
Pages (from-to)	17130-17134
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	57
Issue number	52
DOIs	https://doi.org/10.1002/anie.201810925
State	Published - 21 Dec 2018
Externally published	Yes

Keywords

chiral resolution
chirality
homochiral
membrane separation
metal–organic frameworks

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title = "Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation",

abstract = "Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high-quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework-8 (ZIF-8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l-histidine (l-His), into the framework of ZIF-8. The homochiral l-His-ZIF-8 membrane exhibits a good selectivity for the R-enantiomer of 1-phenylethanol over the S-enantiomer, showing a high enantiomeric excess value up to 76 %.",

keywords = "chiral resolution, chirality, homochiral, membrane separation, metal–organic frameworks",

author = "Chan, {Jun Yong} and Huacheng Zhang and Yada Nolvachai and Yaoxin Hu and Haijin Zhu and Maria Forsyth and Qinfen Gu and Hoke, {David E.} and Xiwang Zhang and Marriot, {Philip J.} and Huanting Wang",

note = "Publisher Copyright: {\textcopyright} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2018",

month = dec,

day = "21",

doi = "10.1002/anie.201810925",

language = "英语",

volume = "57",

pages = "17130--17134",

journal = "Angewandte Chemie - International Edition",

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TY - JOUR

T1 - Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation

AU - Chan, Jun Yong

AU - Zhang, Huacheng

AU - Nolvachai, Yada

AU - Hu, Yaoxin

AU - Zhu, Haijin

AU - Forsyth, Maria

AU - Gu, Qinfen

AU - Hoke, David E.

AU - Zhang, Xiwang

AU - Marriot, Philip J.

AU - Wang, Huanting

PY - 2018/12/21

Y1 - 2018/12/21

N2 - Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high-quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework-8 (ZIF-8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l-histidine (l-His), into the framework of ZIF-8. The homochiral l-His-ZIF-8 membrane exhibits a good selectivity for the R-enantiomer of 1-phenylethanol over the S-enantiomer, showing a high enantiomeric excess value up to 76 %.

AB - Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high-quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework-8 (ZIF-8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l-histidine (l-His), into the framework of ZIF-8. The homochiral l-His-ZIF-8 membrane exhibits a good selectivity for the R-enantiomer of 1-phenylethanol over the S-enantiomer, showing a high enantiomeric excess value up to 76 %.

KW - chiral resolution

KW - chirality

KW - homochiral

KW - membrane separation

KW - metal–organic frameworks

UR - http://www.scopus.com/inward/record.url?scp=85057297597&partnerID=8YFLogxK

U2 - 10.1002/anie.201810925

DO - 10.1002/anie.201810925

M3 - 文章

C2 - 30370963

AN - SCOPUS:85057297597

SN - 1433-7851

VL - 57

SP - 17130

EP - 17134

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 52

ER -

Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation

Abstract

Keywords

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