Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation

Jun Yong Chan, Huacheng Zhang*, Yada Nolvachai, Yaoxin Hu, Haijin Zhu, Maria Forsyth, Qinfen Gu, David E. Hoke, Xiwang Zhang, Philip J. Marriot, Huanting Wang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

96 Scopus citations

Abstract

Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high-quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework-8 (ZIF-8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l-histidine (l-His), into the framework of ZIF-8. The homochiral l-His-ZIF-8 membrane exhibits a good selectivity for the R-enantiomer of 1-phenylethanol over the S-enantiomer, showing a high enantiomeric excess value up to 76 %.

Original languageEnglish
Pages (from-to)17130-17134
Number of pages5
JournalAngewandte Chemie - International Edition
Volume57
Issue number52
DOIs
StatePublished - 21 Dec 2018
Externally publishedYes

Keywords

  • chiral resolution
  • chirality
  • homochiral
  • membrane separation
  • metal–organic frameworks

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