Abstract
Human Edwardsiella tarda infections often manifest as gastroenteritis, but can become systemic and potentially lethal. E. tarda uses virulence factors that include type III and type VI secretion systems, quorum sensing, two-component systems, and exoenzymes to gain entry into and survive within the host. Better understanding of interactions between these factors will lead to the development of novel antimicrobials against E. tarda and other enterics.
Original language | English |
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Pages (from-to) | 26-34 |
Number of pages | 9 |
Journal | Microbes and Infection |
Volume | 14 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2012 |
Externally published | Yes |
Keywords
- Bacterial secretion systems
- Edwardsiella tarda
- Human gastroenteritis
- T3SS and T6SS
- Virulence mechanisms
- Virulence regulation