TY - JOUR
T1 - Bioactive compounds and biological functions of garlic (allium sativum L.)
AU - Shang, Ao
AU - Cao, Shi Yu
AU - Xu, Xiao Yu
AU - Gan, Ren You
AU - Tang, Guo Yi
AU - Corke, Harold
AU - Mavumengwana, Vuyo
AU - Li, Hua Bin
N1 - Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
PY - 2019/7
Y1 - 2019/7
N2 - Garlic (Allium sativum L.) is a widely consumed spice in the world. Garlic contains diverse bioactive compounds, such as allicin, alliin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, ajoene, and S-allyl-cysteine. Substantial studies have shown that garlic and its bioactive constituents exhibit antioxidant, anti-inflammatory, antibacterial, antifungal, immunomodulatory, cardiovascular protective, anticancer, hepatoprotective, digestive system protective, anti-diabetic, anti-obesity, neuroprotective, and renal protective properties. In this review, the main bioactive compounds and important biological functions of garlic are summarized, highlighting and discussing the relevant mechanisms of actions. Overall, garlic is an excellent natural source of bioactive sulfur-containing compounds and has promising applications in the development of functional foods or nutraceuticals for the prevention and management of certain diseases.
AB - Garlic (Allium sativum L.) is a widely consumed spice in the world. Garlic contains diverse bioactive compounds, such as allicin, alliin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, ajoene, and S-allyl-cysteine. Substantial studies have shown that garlic and its bioactive constituents exhibit antioxidant, anti-inflammatory, antibacterial, antifungal, immunomodulatory, cardiovascular protective, anticancer, hepatoprotective, digestive system protective, anti-diabetic, anti-obesity, neuroprotective, and renal protective properties. In this review, the main bioactive compounds and important biological functions of garlic are summarized, highlighting and discussing the relevant mechanisms of actions. Overall, garlic is an excellent natural source of bioactive sulfur-containing compounds and has promising applications in the development of functional foods or nutraceuticals for the prevention and management of certain diseases.
KW - Anticancer
KW - Antimicrobial
KW - Antioxidant
KW - Cardiovascular protection
KW - Garlic
KW - Health benefits
KW - Organic sulfides
KW - Phytochemicals
UR - http://www.scopus.com/inward/record.url?scp=85069218155&partnerID=8YFLogxK
U2 - 10.3390/foods8070246
DO - 10.3390/foods8070246
M3 - 文献综述
AN - SCOPUS:85069218155
SN - 2304-8158
VL - 8
JO - Foods
JF - Foods
IS - 7
M1 - 246
ER -