Synthesis and characterization of ph sensitive core-shell-corona micelles of poly(styrene-block-2-vinylpyridine-block-ethylene oxide) ABC triblock copolymer in aqueous solutions

TY - JOUR

T1 - Synthesis and characterization of ph sensitive core-shell-corona micelles of poly(styrene-block-2-vinylpyridine-block-ethylene oxide) ABC triblock copolymer in aqueous solutions

AU - Bharatiya, Bhavesh

AU - Yusa, Shin Ichi

AU - Aswal, Vinod

AU - Abezgauz, Ludmila

AU - Danino, Dganit

AU - Bahadur, Pratap

PY - 2011

Y1 - 2011

N2 - The coreshellcorona forming ABC triblock copolymer poly(styrene-block-2- vinylpyridine-block-ethylene oxide), PSP2VPPEO, was synthesized using reversible addition fragmentation chain transfer (RAFT) radical polymerization and characterized by NMR and GPC as PS13P2VP62PEO 47. The aggregation behavior in aqueous solution as a function of pH and temperature was studied. Turbidity measurements were used to monitor the effects associated with change in pH. The pH-sensitive P2VP block (insoluble above pH >5) and resultant protonation/deprotonation phenomenon plays decisive role in the aggregation. We found that spherical micelles of considerably low aggregation number form at pH >5. SANS and DLS characterization indicate the micelles' size and spherical shape remained virtually constant in the pH range 1 to 5. The size and shape were further confirmed by cryo-TEM.

AB - The coreshellcorona forming ABC triblock copolymer poly(styrene-block-2- vinylpyridine-block-ethylene oxide), PSP2VPPEO, was synthesized using reversible addition fragmentation chain transfer (RAFT) radical polymerization and characterized by NMR and GPC as PS13P2VP62PEO 47. The aggregation behavior in aqueous solution as a function of pH and temperature was studied. Turbidity measurements were used to monitor the effects associated with change in pH. The pH-sensitive P2VP block (insoluble above pH >5) and resultant protonation/deprotonation phenomenon plays decisive role in the aggregation. We found that spherical micelles of considerably low aggregation number form at pH >5. SANS and DLS characterization indicate the micelles' size and spherical shape remained virtually constant in the pH range 1 to 5. The size and shape were further confirmed by cryo-TEM.

UR - http://www.scopus.com/inward/record.url?scp=81255172188&partnerID=8YFLogxK

U2 - 10.1246/bcsj.20110184

DO - 10.1246/bcsj.20110184

M3 - 文章

AN - SCOPUS:81255172188

SN - 0009-2673

VL - 84

SP - 1227

EP - 1233

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

IS - 11

ER -