Error-Compensated Kinetic Determinations by Detecting the intermediate Product in Successive Reactions, without Prior Knowledge of Reaction Constants

Israel Schechter

doi:10.1021/ac00013a023

Error-Compensated Kinetic Determinations by Detecting the intermediate Product in Successive Reactions, without Prior Knowledge of Reaction Constants

Israel Schechter^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The paper describes an algorithm for the determination of substrate A and reaction coefficients k₁, and k₂ in the successive reaction A → k B → k C, by the kinetic detection of B. The algorithm is studied by using simulated data with different levels of superimposed noise and different rate constants, initial concentrations, and data densities. The algorithm Is evaluated mainly for determination of A but also for finding the reaction constants. This algorithm was found to be suitable for a wide range of concentrations and rate constant values, and in many cases a prior estimate of the order of magnitude of the parameters is sufficient.

Original language	English
Pages (from-to)	1303-1307
Number of pages	5
Journal	Analytical Chemistry
Volume	63
Issue number	13
DOIs	https://doi.org/10.1021/ac00013a023
State	Published - 1 Jul 1991
Externally published	Yes

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title = "Error-Compensated Kinetic Determinations by Detecting the intermediate Product in Successive Reactions, without Prior Knowledge of Reaction Constants",

abstract = "The paper describes an algorithm for the determination of substrate A and reaction coefficients k1, and k2 in the successive reaction A → k B → k C, by the kinetic detection of B. The algorithm is studied by using simulated data with different levels of superimposed noise and different rate constants, initial concentrations, and data densities. The algorithm Is evaluated mainly for determination of A but also for finding the reaction constants. This algorithm was found to be suitable for a wide range of concentrations and rate constant values, and in many cases a prior estimate of the order of magnitude of the parameters is sufficient.",

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year = "1991",

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N2 - The paper describes an algorithm for the determination of substrate A and reaction coefficients k1, and k2 in the successive reaction A → k B → k C, by the kinetic detection of B. The algorithm is studied by using simulated data with different levels of superimposed noise and different rate constants, initial concentrations, and data densities. The algorithm Is evaluated mainly for determination of A but also for finding the reaction constants. This algorithm was found to be suitable for a wide range of concentrations and rate constant values, and in many cases a prior estimate of the order of magnitude of the parameters is sufficient.

AB - The paper describes an algorithm for the determination of substrate A and reaction coefficients k1, and k2 in the successive reaction A → k B → k C, by the kinetic detection of B. The algorithm is studied by using simulated data with different levels of superimposed noise and different rate constants, initial concentrations, and data densities. The algorithm Is evaluated mainly for determination of A but also for finding the reaction constants. This algorithm was found to be suitable for a wide range of concentrations and rate constant values, and in many cases a prior estimate of the order of magnitude of the parameters is sufficient.

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M3 - 文章

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JO - Analytical Chemistry

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ER -

Error-Compensated Kinetic Determinations by Detecting the intermediate Product in Successive Reactions, without Prior Knowledge of Reaction Constants

Abstract

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