Comparative proteomic analysis of extracellular proteins of Edwardsiella tarda

Y. P. Tan, Q. Lin, X. H. Wang, S. Joshi, C. L. Hew, K. Y. Leung*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

A comparison of extracellular proteins of virulent and avirulent Edwardsiella tarda strains revealed several major, virulent-strain-specific proteins. Proteomic analysis identified two of the proteins in the virulent strain PPD130/91 as flagellin and SseB, which are virulence factors in bacterial pathogens. PCR amplification and DNA sequencing confirmed the presence of the genes that encode these proteins. Our results clearly demonstrated the potency of the proteomic approach in identifying virulence factors.

Original languageEnglish
Pages (from-to)6475-6480
Number of pages6
JournalInfection and Immunity
Volume70
Issue number11
DOIs
StatePublished - Nov 2002
Externally publishedYes

Fingerprint Dive into the research topics of 'Comparative proteomic analysis of extracellular proteins of Edwardsiella tarda'. Together they form a unique fingerprint.

Cite this