Comparative analysis of bioactivities of four Polygonum species

TY - JOUR

T1 - Comparative analysis of bioactivities of four Polygonum species

AU - Huang, Wu Yang

AU - Cai, Yi Zhong

AU - Xing, Jie

AU - Corke, Harold

AU - Sun, Mei

PY - 2008/1

Y1 - 2008/1

N2 - Many species of Polygonum are rich in bioactive constituents, which contribute to a wide range of medicinal properties. In this study, we assessed the scavenging activity against ABTS.+ and hydroxyl radicals, chelating activity against Fe2+, xanthine oxidase inhibition, antimicrobial activity, and total contents of phenolics and flavonoids in the extracts of leaves and stems or whole plants from four medicinal Polygonum species. Total antioxidant capacities and phenolic contents of Polygonum capitatum, Polygonum chinensis, Polygonum cuspidatum, and Polygonum multiflorum were 74.60, 53.66, 56.22, and 14.34 mmol trolox/100 g dry weight (DW), and 8.69, 4.15, 6.33, and 1.27 g gallic acid/100 g DW, respectively, significantly higher than those of five dietary vegetables, fruits and spices (spring onion, broccoli, orange, carrot, and ginger). Major bioactive constituents in the tested plant extracts were also investigated using LC-MS. They were mainly phenolic compounds, e.g., flavonoids, phenolic acids and their derivatives, tannins, stilbenes, and anthraquinones. This study shows that, in addition to their roots, the leaves and stems of P. cuspidatum and P. capitatum also exhibit potent antioxidant properties and are a potential resource of natural bioactive antioxidants.

AB - Many species of Polygonum are rich in bioactive constituents, which contribute to a wide range of medicinal properties. In this study, we assessed the scavenging activity against ABTS.+ and hydroxyl radicals, chelating activity against Fe2+, xanthine oxidase inhibition, antimicrobial activity, and total contents of phenolics and flavonoids in the extracts of leaves and stems or whole plants from four medicinal Polygonum species. Total antioxidant capacities and phenolic contents of Polygonum capitatum, Polygonum chinensis, Polygonum cuspidatum, and Polygonum multiflorum were 74.60, 53.66, 56.22, and 14.34 mmol trolox/100 g dry weight (DW), and 8.69, 4.15, 6.33, and 1.27 g gallic acid/100 g DW, respectively, significantly higher than those of five dietary vegetables, fruits and spices (spring onion, broccoli, orange, carrot, and ginger). Major bioactive constituents in the tested plant extracts were also investigated using LC-MS. They were mainly phenolic compounds, e.g., flavonoids, phenolic acids and their derivatives, tannins, stilbenes, and anthraquinones. This study shows that, in addition to their roots, the leaves and stems of P. cuspidatum and P. capitatum also exhibit potent antioxidant properties and are a potential resource of natural bioactive antioxidants.

KW - Antimicrobial activity

KW - Antioxidant capacity

KW - Phenolic compounds

KW - Polygonaceae

KW - Polygonum

KW - Xanthine oxidase inhibition

UR - http://www.scopus.com/inward/record.url?scp=39149137792&partnerID=8YFLogxK

U2 - 10.1055/s-2007-993759

DO - 10.1055/s-2007-993759

M3 - 文章

C2 - 18067063

AN - SCOPUS:39149137792

VL - 74

SP - 43

EP - 49

JO - Planta Medica

JF - Planta Medica

SN - 0032-0943

IS - 1

ER -