TY - JOUR
T1 - Comparative analysis of bioactivities of four Polygonum species
AU - Huang, Wu Yang
AU - Cai, Yi Zhong
AU - Xing, Jie
AU - Corke, Harold
AU - Sun, Mei
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2008/1
Y1 - 2008/1
N2 - Many species of Polygonum are rich in bioactive constituents, which contribute to a wide range of medicinal properties. In this study, we assessed the scavenging activity against ABTS.+ and hydroxyl radicals, chelating activity against Fe2+, xanthine oxidase inhibition, antimicrobial activity, and total contents of phenolics and flavonoids in the extracts of leaves and stems or whole plants from four medicinal Polygonum species. Total antioxidant capacities and phenolic contents of Polygonum capitatum, Polygonum chinensis, Polygonum cuspidatum, and Polygonum multiflorum were 74.60, 53.66, 56.22, and 14.34 mmol trolox/100 g dry weight (DW), and 8.69, 4.15, 6.33, and 1.27 g gallic acid/100 g DW, respectively, significantly higher than those of five dietary vegetables, fruits and spices (spring onion, broccoli, orange, carrot, and ginger). Major bioactive constituents in the tested plant extracts were also investigated using LC-MS. They were mainly phenolic compounds, e.g., flavonoids, phenolic acids and their derivatives, tannins, stilbenes, and anthraquinones. This study shows that, in addition to their roots, the leaves and stems of P. cuspidatum and P. capitatum also exhibit potent antioxidant properties and are a potential resource of natural bioactive antioxidants.
AB - Many species of Polygonum are rich in bioactive constituents, which contribute to a wide range of medicinal properties. In this study, we assessed the scavenging activity against ABTS.+ and hydroxyl radicals, chelating activity against Fe2+, xanthine oxidase inhibition, antimicrobial activity, and total contents of phenolics and flavonoids in the extracts of leaves and stems or whole plants from four medicinal Polygonum species. Total antioxidant capacities and phenolic contents of Polygonum capitatum, Polygonum chinensis, Polygonum cuspidatum, and Polygonum multiflorum were 74.60, 53.66, 56.22, and 14.34 mmol trolox/100 g dry weight (DW), and 8.69, 4.15, 6.33, and 1.27 g gallic acid/100 g DW, respectively, significantly higher than those of five dietary vegetables, fruits and spices (spring onion, broccoli, orange, carrot, and ginger). Major bioactive constituents in the tested plant extracts were also investigated using LC-MS. They were mainly phenolic compounds, e.g., flavonoids, phenolic acids and their derivatives, tannins, stilbenes, and anthraquinones. This study shows that, in addition to their roots, the leaves and stems of P. cuspidatum and P. capitatum also exhibit potent antioxidant properties and are a potential resource of natural bioactive antioxidants.
KW - Antimicrobial activity
KW - Antioxidant capacity
KW - Phenolic compounds
KW - Polygonaceae
KW - Polygonum
KW - Xanthine oxidase inhibition
UR - http://www.scopus.com/inward/record.url?scp=39149137792&partnerID=8YFLogxK
U2 - 10.1055/s-2007-993759
DO - 10.1055/s-2007-993759
M3 - 文章
C2 - 18067063
AN - SCOPUS:39149137792
VL - 74
SP - 43
EP - 49
JO - Planta Medica
JF - Planta Medica
SN - 0032-0943
IS - 1
ER -