Cellular responses evoked by different surface characteristics of intraosseous titanium implants

Liviu Feller*, Yusuf Jadwat, Razia A.G. Khammissa, Robin Meyerov, Israel Schechter, Johan Lemmer

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations

Abstract

The properties of biomaterials, including their surface microstructural topography and their surface chemistry or surface energy/wettability, affect cellular responses such as cell adhesion, proliferation, and migration. The nanotopography of moderately rough implant surfaces enhances the production of biological mediators in the peri-implant microenvironment with consequent recruitment of differentiating osteogenic cells to the implant surface and stimulates osteogenic maturation. Implant surfaces with moderately rough topography and with high surface energy promote osteogenesis, increase the ratio of bone-to-implant contact, and increase the bonding strength of the bone to the implant at the interface. Certain features of implant surface chemistry are also important in enhancing peri-implant bone wound healing. It is the purpose of this paper to review some of the more important features of titanium implant surfaces which have an impact on osseointegration.

Original languageEnglish
Article number171945
JournalBioMed Research International
Volume2015
DOIs
StatePublished - 2015
Externally publishedYes

Fingerprint Dive into the research topics of 'Cellular responses evoked by different surface characteristics of intraosseous titanium implants'. Together they form a unique fingerprint.

Cite this