Pesticide usage and inappropriate disposal of pesticide wastes have been identified as a source of soil as well as surface and groundwater contamination. Currently, there are few options available to small-scale pesticide applicators and homeowners to safely and effectively dispose of pesticide waste. To help alleviate this situation, we are developing a pesticide wastewater clean-up procedure employing biologically-based materials. These materials serve as a sorbent for effective removal of pesticides from aqueous solutions (sorption) and as a matrix on which these sorbed wastes are subsequently degraded by chemical and microbial processes. Relatively high concentrations (5000 mg/L) of formulated chlorpyrifos and metolachlor can be removed using biobased materials of various types. Heat and carbon dioxide production were compared to evaluate the potential of some biobased materials to support an environment for pesticide (bio)degradation.