Biocatalytic implant of Pt nanoclusters into glucose oxidase: A method to electrically wire the enzyme and to transform it from an oxidase to a hydrogenase

Omer Yehezkeli, Sara Raichlin, Ran Tel-Vered, Ellina Kesselman, Dganit Danino, Itamar Willner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The enzyme glucose oxidase (GOx) reduces, in the presence of glucose and under anaerobic conditions, PtCl62- to Pt nanoclusters (NCs) that are implanted in the protein. The assembly of the Pt NC/GOx hybrid on a dithiol monolayer yields an electrically contacted enzyme electrode, and the bioelectrocatalytic oxidation of glucose is activated (turnover rate ca. 2780 ± 70 s-1). The Pt NC/GOx hybrid is also used, under anaerobic conditions, as a biocatalyst for H2 evolution.

Original languageEnglish
Pages (from-to)2816-2819
Number of pages4
JournalJournal of Physical Chemistry Letters
Volume1
Issue number19
DOIs
StatePublished - 7 Oct 2010
Externally publishedYes

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