Research progress on the antibacterial mechanismsofcarvacrol: A mini review

Dan Zhang; Ren You Gan; Ying Ying Ge; Qiong Qiong Yang; Jiao Ge; Hua Bin Li; Harold Corke

doi:10.31989/bchd.v1i6.551

Research progress on the antibacterial mechanismsofcarvacrol: A mini review

Dan Zhang, Ren You Gan^*, Ying Ying Ge, Qiong Qiong Yang, Jiao Ge, Hua Bin Li, Harold Corke

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Background: Carvacrol is an aromatic phenolicterpenoidwidely existingin the volatile oils of thyme, oregano, and some other aromatic plants. Recent studies have found that carvacrol possessesexcellent antibacterial activity. Thus, inorder to provide an updated information about the antibacterial potentials of carvacrolwe summarized recent publications about the antibacterial activity of carvacrol,with special attention paid to its antibacterial molecular mechanisms, includingdisruptingcellmembrane, depleting intracellular ATP, inducing reactive oxygen species, inhibiting efflux pumps, as well as suppressing two important virulence factors:biofilm and quorum sensing.In conclusion, carvacrol is a promising natural antibacterial compound with potential application in food preservation and infection.

Original language	English
Pages (from-to)	71-81
Number of pages	11
Journal	Bioactive Compounds in Health and Disease
Volume	1
Issue number	6
DOIs	https://doi.org/10.31989/bchd.v1i6.551
State	Published - Oct 2018
Externally published	Yes

Keywords

Antibacterialmechanisms
Biofilm
Carvacrol
Quorum sensing

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title = "Research progress on the antibacterial mechanismsofcarvacrol: A mini review",

abstract = "Background: Carvacrol is an aromatic phenolicterpenoidwidely existingin the volatile oils of thyme, oregano, and some other aromatic plants. Recent studies have found that carvacrol possessesexcellent antibacterial activity. Thus, inorder to provide an updated information about the antibacterial potentials of carvacrolwe summarized recent publications about the antibacterial activity of carvacrol,with special attention paid to its antibacterial molecular mechanisms, includingdisruptingcellmembrane, depleting intracellular ATP, inducing reactive oxygen species, inhibiting efflux pumps, as well as suppressing two important virulence factors:biofilm and quorum sensing.In conclusion, carvacrol is a promising natural antibacterial compound with potential application in food preservation and infection.",

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author = "Dan Zhang and Gan, {Ren You} and Ge, {Ying Ying} and Yang, {Qiong Qiong} and Jiao Ge and Li, {Hua Bin} and Harold Corke",

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month = oct,

doi = "10.31989/bchd.v1i6.551",

language = "英语",

volume = "1",

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AU - Zhang, Dan

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AU - Ge, Jiao

AU - Li, Hua Bin

AU - Corke, Harold

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N2 - Background: Carvacrol is an aromatic phenolicterpenoidwidely existingin the volatile oils of thyme, oregano, and some other aromatic plants. Recent studies have found that carvacrol possessesexcellent antibacterial activity. Thus, inorder to provide an updated information about the antibacterial potentials of carvacrolwe summarized recent publications about the antibacterial activity of carvacrol,with special attention paid to its antibacterial molecular mechanisms, includingdisruptingcellmembrane, depleting intracellular ATP, inducing reactive oxygen species, inhibiting efflux pumps, as well as suppressing two important virulence factors:biofilm and quorum sensing.In conclusion, carvacrol is a promising natural antibacterial compound with potential application in food preservation and infection.

AB - Background: Carvacrol is an aromatic phenolicterpenoidwidely existingin the volatile oils of thyme, oregano, and some other aromatic plants. Recent studies have found that carvacrol possessesexcellent antibacterial activity. Thus, inorder to provide an updated information about the antibacterial potentials of carvacrolwe summarized recent publications about the antibacterial activity of carvacrol,with special attention paid to its antibacterial molecular mechanisms, includingdisruptingcellmembrane, depleting intracellular ATP, inducing reactive oxygen species, inhibiting efflux pumps, as well as suppressing two important virulence factors:biofilm and quorum sensing.In conclusion, carvacrol is a promising natural antibacterial compound with potential application in food preservation and infection.

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M3 - 文献综述

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EP - 81

JO - Bioactive Compounds in Health and Disease

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Research progress on the antibacterial mechanismsofcarvacrol: A mini review

Abstract

Keywords

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